Heat Shock Protein
The thermal shock in biochemistry means subjecting the cell to a temperature that goes beyond the optimal temperature range of the cell's function. It refers to the cellular exposure to rapid changes in stress, which may be oxidative stress, toxins, heavy metals, pathogens or just temperature. Temperature-induced, even by a few degrees, can stab the correct folding of the protein. As a result, proteins fold incorrectly and become entangled, which may cause non-specific aggregation.